QuantumCor's endovascular (catheter) device allows the physician to remodel the mitral valve during a minimally invasive cardiac cath lab procedure.  

It's all about collagen

The QuantumCor solution is based on three simple and well understood scientific and clinical facts:

• The mitral valve annulus has a high collagen content

• Heating collagen will cause it to shrink

• Direct application of RF energy to the mitral valve annulus  heats the collagen fibers causing the them to shrink 

The QuantumCor catheter device has a series of electrodes that are placed on the mitral valve annulus.  With the electrodes in firm contact with the annular tissue, energy is delivered using a low temperature protocol.  The annular tissue is heated, the covalent bonds are broken allowing the collagen fibers to shrink, remodeling the valve.    

Effective remodeling

Applying low temperature heat to multiple areas of the posterior leaflet of the mitral valve annulus denatures the collagen, breaks the covalent bonds, allows the fibers to shrink, but does not damage the underlying structure.  While the QuantumCor protocol limits the shrinkage of individual fibers, by treating the annulus from trigone to trigone clinically appropriate remodeling is achieved.

The QuantumCor technology and clinical approach allows the physician to remodel the mitral valve annulus without leaving hardware in the heart or vascular system.